Email this article 
Hide
Show all
Original Research
Abacavir: it’s use and hypersensitivity
Southern African Journal of HIV Medicine | Vol 10, No 4 | a265 |
DOI: https://doi.org/10.4102/sajhivmed.v10i4.265
| © 2009 Helena Rabie, Kristin Lorenc Henning, Pierre Schoeman, Nico de Villiers, G HJ Pretorius, Mark F Cotton
| This work is licensed under CC Attribution 4.0
Submitted: 15 December 2009 | Published: 14 December 2009
Submitted: 15 December 2009 | Published: 14 December 2009
About the author(s)
Helena Rabie,Kristin Lorenc Henning, Department of Paediatrics and Child Health
Pierre Schoeman, PathCare Laboratories, N1 City, Goodwood
Nico de Villiers, PathCare Laboratories, N1 City, Goodwood
G HJ Pretorius,
Mark F Cotton,
Full Text:
PDF (188KB)Abstract
Abacavir, a nucleoside reverse transcriptase inhibitor, is useful in first and second line therapy as well as a substitute for Stavudine and Zidovudine for toxicity. Although safe and well tolerated, a life threatening hypersensitivity reaction can occur. The risk for developing this reaction relates to the presence of specific genotypes especially HLA-B*5701.
Keywords
No related keywords in the metadata.
Metrics
Total abstract views: 2846Total article views: 2560
Crossref Citations
1. Pharmacogenetics and rational drug use around the world
Mary W Roederer, Francisco Sanchez-Giron, Kusha Kalideen, William Kudzi, Howard L McLeod, Wei Zhang
Pharmacogenomics vol: 12 issue: 6 first page: 897 year: 2011
doi: 10.2217/pgs.11.17